RIX4414 (Rotarix): a live attenuated human rotavirus vaccine.
نویسنده
چکیده
report. New York: Oxford University; 2005. 4. Fortes Filho JB, Barros CK, daCostaMC, ProcianoyRS. Results of a program for the prevention of blindness caused by retinopathy of prematurity in southern Brazil. J Pediatr (Rio J). 2007;83:209-16. 5. Gilbert C, Fielder F, Gordillo L, Quinn G, Semiglia R, Visintin P, et al. Characteristics of infants with severe retinopathy of prematurity in countries with low, moderate and high levels of development: implications for screening programs. Pediatrics. 2005;115:e518-25. 6. Section on Ophthalmology American Academy of Pediatrics, American Academy of Ophthalmology, American Association for Pediatric Ophthalmology and Strabismus. Screening examination of premature infants for retinopathy of prematurity. Pediatrics. 2006;117:572-6. Erratum in: Pediatrics. 2006;118:1324. 7. Guidelines for screening examinations for retinopathy of prematurity. Canadian Association of Pediatric Ophthalmologists AdHoc Committee on Standards of Screening Examination for Retinopathy of Prematurity. Can J Ophthalmol. 2000;35:251-2.
منابع مشابه
A rotavirus vaccine for infants: the Asian experience.
INTRODUCTION Severe rotavirus gastroenteritis in children causes significant morbidity worldwide and substantial deaths in developing countries. Hence, a live attenuated vaccine Rotarix was developed with human strain RIX4414 of G1P1A P[8] specificity. RIX4414 trials in infants have begun in developed and developing countries worldwide. An overview of RIX4414 in developed and developing countri...
متن کاملRotarix (RIX4414): an oral human rotavirus vaccine.
Rotavirus is the most common cause of severe gastroenteritis in children younger than 3 years of age worldwide. New rotavirus vaccine candidates were required to confer early protection against the most common rotavirus serotypes and to be well tolerated and not associated with intussusception. RIX4414 is a human-attenuated G1(P8) oral rotavirus vaccine administered in two doses at approximatel...
متن کاملEvaluation of RIX4414, a live, attenuated rotavirus vaccine, in a randomized, double-blind, placebo-controlled phase 2 trial involving 2464 Singaporean infants.
BACKGROUND At present, no rotavirus vaccine is commercially available for use worldwide. Hence, a live, attenuated monovalent vaccine was developed with human strain RIX4414 (G1P1A P[8] specificity). Vaccination trials involving infants are ongoing in developed and developing countries. METHODS This study was a randomized, double-blind, placebo-controlled trial conducted at pediatric hospital...
متن کاملPharmacoeconomic Spotlight on Rotavirus Vaccine RIX4414 (Rotarix™) in Developed Countries
The most common cause of severe diarrhea in infants and young children is rotavirus gastroenteritis (RVGE), which is associated with significant morbidity, healthcare resource use, and direct and indirect costs in industrialized nations. The monovalent rotavirus vaccine RIX4414 (Rotarix™) is administered as a two-dose oral series in infants and has demonstrated protective efficacy against RVGE ...
متن کاملCost-effectiveness analysis of vaccination against rotavirus with RIX4414 in France.
BACKGROUND It is estimated that annually 300 000 cases of rotavirus-induced gastroenteritis (RVGE) occur in children aged up to 5 years in France. A two-dose vaccine against rotavirus infection (RIX4414; Rotarix, GlaxoSmithKline), has been shown to be highly effective against severe RVGE. OBJECTIVE This study evaluated the cost effectiveness of general vaccination against rotavirus using RIX4...
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ورودعنوان ژورنال:
- Jornal de pediatria
دوره 83 3 شماره
صفحات -
تاریخ انتشار 2007